The Haft-Savaran Pb-Zn mineralization zone with the lower Jurassic age is located in the southern basin of Arak and Malayer-Isfahan metallogenic belt of Iran. Based upon the geological map of the Haft-Savaran area, the sandstone and shale of lower Jurassic are the main rocks of Pb-Zn deposit. In this area, 170samples were taken from 33 boreholes, and44 elements were measured by the ICP-MS method. Adaptation of the alteration index and Pb–Zn mineralization was investigated in this work. The model was created based on the Sericitic, Spitz-Darling, Alkali, Hashimoto, and Silicification Indices in all boreholes. This work showed that the Sericite, Hashimoto, Spitz-Darling, and Silicification indices increased around mineralization, and the alkali index decreased around it. Development of the alteration indices indicates that direction of the ore-bearing solution is NE-SW, and that this trend is consistent with the faults in the area. Based upon the 3D models and other data interpretations, Pb–Zn and elements such as Fe, Mn, Cr, and Ni have deposited within the alteration zones.